Recombinant Human MCM5 Protein, GST and His-tagged

• Cat.No.: MCM5-009H
• Product Overview: Purified recombinant protein of full length Human minichromosome maintenance complex component 5 (MCM5), with N-terminal GST and C-terminal HIS tag, was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]
• Source: E. coli
• Species: Human
• Tag: GST and His
• Molecular Mass: 110.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25mM Tris, pH 8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Gene Information

• Gene Name: MCM5 minichromosome maintenance complex component 5 [ Homo sapiens ]
• Official Symbol: MCM5
• Synonyms: MCM5; minichromosome maintenance complex component 5; CDC46, MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae), minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46); DNA replication licensing factor MCM5; CDC46 homolog; minichromosome maintenance deficient 5 (cell division cycle 46); MCM5 minichromosome maintenance deficient 5, cell division cycle 46; CDC46; P1-CDC46; MGC5315
• Gene ID: 4174
• mRNA Refseq: NM_006739
• Protein Refseq: NP_006730
• MIM: 602696
• UniProt ID: P33992