| Description : |
DNA replication is a carefully orchestrated process involving many proteins that assemble at origins of replication. Among these are the 6 proteins of the minichromosome maintenance (MCM) complex (e.g., MCM2; MIM 116945), which form a hexamer. Each MCM subunit performs an essential function in initiation and elongation of DNA replication. MCMBP can replace MCM2 in the MCM complex, thus forming an alternative MCM hexamer (Sakwe et al., 2007 [PubMed 17296731]). |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Form : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Molecular Mass : |
99.1 kDa |
| AA Sequence : |
MPCGEDWLSHPLGIVQGFFAQNGVN PDWEKKVIEYFKEKLKENNAPKWVP SLNEVPLHYLKPNSFVKFRCMIQDM FDPEFYMGVYETVNQNTKAHVLHFG KYRDVAECGPQQELDLNSPRNTTLE RQTFYCVPVPGESTWVKEAYVNANQ ARVSPSTSYTPSRHKRSYEDDDDMD LQPNKQKDQHAGARQAGSVGGLQWC GEPKRLETEASTGQQLNSLNLSSPF DLNFPLPGEKGPACLVKVYEDWDCF KVNDILELYGILSVDPVLSILNNDE RDASALLDPMECTDTAEEQRVHSPP ASLVPRIHVILAQKLQHINPLLPAC LNKEESKTFVSSFMSELSPVRAELL GFLTHALLGDSLAAEYLILHLISTV YTRRDVLPLGKFTVNLSGCPRNSTF TEHLYRIIQHLVPASFRLQMTIENM NHLKFIPHKDYTANRLVSGLLQLPS NTSLVIDETLLEQGQLDTPGVHNVT ALSNLITWQKVDYDFSYHQMEFPCN INVFITSEGRSLLPADCQIHLQPQL IPPNMEEYMNSLLSAVLPSVLNKFR IYLTLLRFLEYSISDEITKAVEDDF VEMRKNDPQSITADDLHQLLVVARC LSLSAGQTTLSRERWLRAKQLESLR RTRLQQQKCVNGNEL |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
