Recombinant Human MDM4 Protein, GST-tagged
Cat.No. : | MDM4-4493H |
Product Overview : | Human MDM4 full-length ORF ( NP_002384.2, 1 a.a. - 490 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 81.3 kDa |
AA Sequence : | MTSFSTSAQCSTSDSACRISPGQIN QVRPKLPLLKILHAAGAQGEMFTVK EVMHYLGQYIMVKQLYDQQEQHMVY CGGDLLGELLGRQSFSVKDPSPLYD MLRKNLVTLATATTDAAQTLALAQD HSMDIPSQDQLKQSAEESSTSRKRT TEDDIPTLPTSEHKCIHSREDEDLI ENLAQDETSRLDLGFEEWDVAGLPW WFLGNLRSNYTPRSNGSTDLQTNQD VGTAIVSDTTDDLWFLNESVSEQLG VGIKVEAADTEQTSEEVGKVSDKKV IEVGKNDDLEDSKSLSDDTDVEVTS EDEWQCTECKKFNSPSKRYCFRCWA LRKDWYSDCSKLTHSLSTSDITAIP EKENEGNDVPDCRRTISAPVVRPKD AYIKKENSKLFDPCNSVEFLDLAHS SESQETISSMGEQLDNLSEQRTDTE NMEDCQNLLKPCSLCEKRPRDGNII HGRTGHLVTCFHCARRLKKAGASCP ICKKEIQLVIKVFIA |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MDM4 Mdm4 p53 binding protein homolog (mouse) [ Homo sapiens ] |
Official Symbol : | MDM4 |
Synonyms : | MDM4; Mdm4 p53 binding protein homolog (mouse); Mdm4, transformed 3T3 cell double minute 4, p53 binding protein (mouse) , mouse double minute 4, human homolog of; p53 binding protein; protein Mdm4; MDMX; protein Mdmx; MDM4-related protein 1; mdm2-like p53-binding protein; double minute 4, human homolog of; p53-binding protein; Mdm4, transformed 3T3 cell double minute 4, p53 binding protein; HDMX; MRP1; MGC132766; DKFZp781B1423; |
Gene ID : | 4194 |
mRNA Refseq : | NM_001204171 |
Protein Refseq : | NP_001191100 |
MIM : | 602704 |
UniProt ID : | O15151 |
Products Types
◆ Recombinant Protein | ||
MDM4-3287R | Recombinant Rat MDM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
MDM4-0091H | Recombinant Human MDM4 Protein (T2-A490), His tagged | +Inquiry |
MDM4-0090H | Recombinant Human MDM4 Protein (T2-A490), Tag Free | +Inquiry |
MDM4-5433M | Recombinant Mouse MDM4 Protein, His (Fc)-Avi-tagged | +Inquiry |
MDM4-4386H | Recombinant Human MDM4 protein, His -tagged | +Inquiry |
◆ Lysates | ||
MDM4-4403HCL | Recombinant Human MDM4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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