Recombinant Human MFNG Protein, GST-tagged

• Cat.No.: MFNG-4379H
• Product Overview: Human MFNG full-length ORF ( NP_002396.2, 1 a.a. - 321 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 62.6 kDa
• AA Sequence: MQCRLPRGLAGALLTLLCMGLLCLR YHLNLSPQRVQGTPELSQPNPGPPK LQLHDVFIAVKTTRAFHRLRLELLL DTWVSRTREQTFVFTDSPDKGLQER LGSHLVVTNCSAEHSHPALSCKMAA EFDTFLASGLRWFCHVDDDNYVNPR ALLQLLRAFPLARDVYVGRPSLNRP IHASEPQPHNRTRLVQFWFATGGAG FCINRKLALKMAPWASGSRFMDTSA LIRLPDDCTMGYIIECKLGGRLQPS PLFHSHLETLQLLRTAQLPEQVTLS YGVFEGKLNVIKLQGPFSPEEDPSR FRSLHCLLYPDTPWCPQLGAR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [ Homo sapiens ]
• Official Symbol: MFNG
• Synonyms: MFNG; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; manic fringe (Drosophila) homolog , manic fringe homolog (Drosophila); beta-1,3-N-acetylglucosaminyltransferase manic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
• Gene ID: 4242
• mRNA Refseq: NM_001166343
• Protein Refseq: NP_001159815
• MIM: 602577
• UniProt ID: O00587