Recombinant Human MFNG Protein, GST-tagged

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Recombinant Human MFNG Protein, GST-tagged

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Cat.No. : MFNG-4379H
Product Overview : Human MFNG full-length ORF ( NP_002396.2, 1 a.a. - 321 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene is a member of the fringe gene family which also includes Radical and Lunatic fringe. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta1,3 N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 62.6 kDa
AA Sequence : MQCRLPRGLA GALLTLLCMG LLCLRYHLNL SPQRVQGTPE LSQPNPGPPK LQLHDVFIAV KTTRAFHRLR LELLLDTWVS RTREQTFVFT DSPDKGLQER LGSHLVVTNC SAEHSHPALS CKMAAEFDTF LASGLRWFCH VDDDNYVNPR ALLQLLRAFP LARDVYVGRP SLNRPIHASE PQPHNRTRLV QFWFATGGAG FCINRKLALK MAPWASGSRF MDTSALIRLP DDCTMGYIIE CKLGGRLQPS PLFHSHLETL QLLRTAQLPE QVTLSYGVFE GKLNVIKLQG PFSPEEDPSR FRSLHCLLYP DTPWCPQLGA R
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue

Gene Name : MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [ Homo sapiens ]
Official Symbol : MFNG
Synonyms : MFNG; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; manic fringe (Drosophila) homolog , manic fringe homolog (Drosophila); beta-1,3-N-acetylglucosaminyltransferase manic fringe; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase;
Gene ID : 4242
mRNA Refseq : NM_001166343
Protein Refseq : NP_001159815
MIM : 602577
UniProt ID : O00587

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