Recombinant Human MFSD8 Protein

• Cat.No.: MFSD8-4372H
• Product Overview: Human MFSD8 full-length ORF (ADZ15480.1) recombinant protein without tag.

Specification

• Description: This gene encodes a ubiquitous integral membrane protein that contains a transporter domain and a major facilitator superfamily (MFS) domain. Other members of the major facilitator superfamily transport small solutes through chemiosmotic ion gradients. The substrate transported by this protein is unknown. The protein likely localizes to lysosomal membranes. Mutations in this gene are correlated with a variant form of late infantile-onset neuronal ceroid lipofuscinoses (vLINCL). [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 57 kDa
• AA Sequence: MAGLRNESEQEPLLGDTPGSREWDI LETEEHYKSRWRSIRILYLTMFLSS VGFSVVMMSIWPYLQKIDPTADTSF LGWVIASYSLGQMVASPIFGLWSNY RPRKEPLIVSILISVAANCLYAYLH IPASHNKYYMLVARGLLGIGAGNVA VVRSYTAGATSLQERTSSMANISMC QALGFILGPVFQTCFTFLGEKGVTW DVIKLQINMYTTPVLLSAFLGILNI ILILAILREHRVDDSGRQCKSINFE EASTDEAQVPQGNIDQVAVVAINVL FFVTLFIFALFETIITPLTMDMYAW TQEQAVLYNGIILAALGVEAVVIFL GVKLLSKKIGERAILLGGLIVVWVG FFILLPWGNQFPKIQWEDLHNNSIP NTTFGEIIIGLWKSPMEDDNERPTG CSIEQAWCLYTPVIHLAQFLTSAVL IGLGYPVCNLMSYTLYSKILGPKPQ GVYMGWLTASGSGARILGPMFISQV YAHWGPRWAFSLVCGIIVLTITLLG VVYKRLIALSVRYGRIQE
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: MFSD8 major facilitator superfamily domain containing 8 [ Homo sapiens ]
• Official Symbol: MFSD8
• Synonyms: MFSD8; major facilitator superfamily domain containing 8; ceroid lipofuscinosis, neuronal 7, late infantile, variant , CLN7; major facilitator superfamily domain-containing protein 8; MGC33302; ceroid-lipofuscinosis neuronal protein 7; ceroid-lipofuscinosis, neuronal 7, late infantile; CLN7
• Gene ID: 256471
• mRNA Refseq: NM_152778
• Protein Refseq: NP_689991
• MIM: 611124
• UniProt ID: Q8NHS3