Recombinant Human MGAT2 Protein, His-tagged

• Cat.No.: MGAT2-001H
• Product Overview: Recombinant Human MGAT2 Protein (427aa, 30-447aa) with His tag was expressed in insect cells.

Specification

• Description: The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.
• Source: Insect cells
• Species: Human
• Tag: His
• Form: Liquid
• Molecular Mass: 49.3kDa
• Endotoxin: < 1.0 EU per 1 μg of protein (determined by LAL method)
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Notes: For research use only. This product is not intended or approved for human, diagnostics or veterinary use.
• Storage: Can be stored at +2 centigrade to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/mL (determined by Absorbance at 280nm)
• Storage Buffer: In 20mM Tris-HCl (pH 7.5) containing 10% glycerol, 0.15M NaCl, 1mM DTT.

Gene Information

• Gene Name: MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [ Homo sapiens (human) ]
• Official Symbol: MGAT2
• Synonyms: MGAT2; mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; GNT2; CDG2A; CDGS2; GNT-II; GLCNACTII; alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Beta-1,2-N-acetylglucosaminyltransferase II; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II; glcNAc-T II; mannoside acetylglucosaminyltransferase 2; EC 2.4.1.143
• Gene ID: 4247
• mRNA Refseq: NM_002408
• Protein Refseq: NP_002399
• MIM: 602616
• UniProt ID: Q10469