Recombinant Human MICU1 Protein, GST-tagged

• Cat.No.: MICU1-5141H
• Product Overview: Human CBARA1 full-length ORF ( AAH04190.1, 1 a.a. - 476 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 80.8 kDa
• AA Sequence: MFRLNSLSALAELAVGSRWYHGGSQ PIQIRRRLMMVAFLGASAVTASTGL LWKRAHAESPPCVDNLKSDIGDKGK NKDEGDVCNHEKKTADLAPHPEEKK KKRSGFRDRKVMEYENRIRAYSTPD KIFRYFATLKVISEPGEAEVFMTPE DFVRSITPNEKQPEHLGLDQYIIKR FDGKKISQEREKFADEGSIFYTLGE CGLISFSDYIFLTTVLSTPQRNFEI AFKMFDLNGDGEVDMEEFEQVQSII RSQTSMGMRHRDRPTTGNTLKSGLC SALTTYFFGADLKGKLTIKNFLEFQ RKLQHDVLKLEFERHDPVDGRITER QFGGMLLAYSGVQSKKLTAMQRQLK KHFKEGKGLTFQEVENFFTFLKNIN DVDTALSFYHMAGASLDKVTMQQVA RTVAKVELSDHVCDVVFALFDCDGN GELSNKEFVSIMKQRLMRGLEKPKD MGFTRLMQAMWKCAQETAWDFALPK Q
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MICU1 mitochondrial calcium uptake 1 [ Homo sapiens (human) ]
• Official Symbol: MICU1
• Synonyms: CBARA1; MICU1; mitochondrial calcium uptake 1; CALC; EFHA3; MPXPS; calcium uptake protein 1, mitochondrial; ara CALC; atopy-related autoantigen CALC; calcium-binding atopy-related autoantigen 1
• Gene ID: 10367
• mRNA Refseq: NM_001195518
• Protein Refseq: NP_001182447
• MIM: 605084
• UniProt ID: Q9BPX6