Recombinant Human MIF Protein

• Cat.No.: MIF-033H
• Product Overview: Recombinant human MIF protein without tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Description: This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
• Molecular Mass: 12.6 kDa
• Purity: ≥95% as determined by SDS-PAGE
• Unit Definition: One unit is defined as the amount of enzyme required to tautomerize 1 nmole of L-dopachrome (5,6-dihydroxyindole-2-carboxylate methyl ester) per minute at 21 centigrade in 40 mM Bis-Tris, pH 6.2, 0.8 mM EDTA, containing 260 μM L-dopachrome methyl ester, and 510 μM sodium periodate.
• Stability: ≥ 1 year
• Storage: At -80 centigrade.

Gene Information

• Gene Name: MIF macrophage migration inhibitory factor [ Homo sapiens (human) ]
• Official Symbol: MIF
• Synonyms: MIF; macrophage migration inhibitory factor; GIF; GLIF; MMIF; macrophage migration inhibitory factor; L-dopachrome isomerase; L-dopachrome tautomerase; epididymis secretory sperm binding protein; macrophage migration inhibitory factor (glycosylation-inhibiting factor); phenylpyruvate tautomerase; EC 5.3.2.1; EC 5.3.3.12
• Gene ID: 4282
• mRNA Refseq: NM_002415
• Protein Refseq: NP_002406
• MIM: 153620
• UniProt ID: P14174