Recombinant Human MLPH Protein, GST-tagged MLPH-5395H

Recombinant Human MLPH Protein, GST-tagged

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Recombinant Human MLPH Protein, GST-tagged

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Cat.No. : MLPH-5395H
Product Overview : Human MLPH full-length ORF ( NP_077006.1, 1 a.a. - 600 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 92.3 kDa
AA Sequence : MGKKLDLSKLTDEEA QHVLEVVQRDFDLRR KEEERLEALKGKIKK ESSKRELLSDTAHLN ETHCARCLQPYQLLV NSKRQCLECGLFTCK SCGRVHPEEQGWICD PCHLARVVKIGSLEW YYEHVKARFKRFGSA KVIRSLHGRLQGGAG PELISEERSGDSDQT DEDGEPGSEAQAQAQ PFGSKKKRLLSVHDF DFEGDSDDSTQPQGH SLHLSSVPEARDSPQ SLTDESCSEKAAPHK AEGLEEADTGASGCH SHPEEQPTSISPSRH GALAELCPPGGSHRM ALGTAAALGSNVIRN EQLPLQYLADVDTSD EESIRAHVMASHHSK RRGRASSESQIFELN KHISAVECLLTYLEN TVVPPLAKGLGAGVR TEADVEEEALRRKLE ELTSNVSDQETSSEE EEAKDEKAEPNRDKS VGPLPQADPEVGTAA HQTNRQEKSPQDPGD PVQYNRTTDEELSEL EDRVAVTASEVQQAE SEVSDIESRIAALRA AGLTVKPSGKPRRKS NLPIFLPRVAGKLGK RPEDPNADPSSEAKA MAVPYLLRRKFSNSL KSQGKDDDSFDRKSV YRGSLTQRNPNARKG MASHTFAKPVVAHQS
Applications : Antibody Production
Functional Study
Compound Screening
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MLPH melanophilin [ Homo sapiens ]
Official Symbol : MLPH
Synonyms : MLPH; melanophilin; exophilin 3; l(1) 3Rk; l1Rk3; ln; Slac 2a; exophilin-3; synaptotagmin-like protein 2a; slp homolog lacking C2 domains a; SLAC2-A; MGC2771; MGC59733;
Gene ID : 79083
mRNA Refseq : NM_001042467
Protein Refseq : NP_001035932
MIM : 606526
UniProt ID : Q9BV36

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