Recombinant Human MMEL1 Protein, GST-tagged

• Cat.No.: MMEL1-5411H
• Product Overview: Human MMEL1 full-length ORF ( AAI01031.1, 1 a.a. - 779 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 115.7 kDa
• AA Sequence: MGKSEGPVGMVESAGRAGQKRPGFL EGGLLLLLLLVTAALVALGVLYADR RGKQLPRLASRLCFLQEERTFVKRK PRGIPEAQEVSEVCTTPGCVIAAAR ILQNMDPTTEPCDDFYQFACGGWLR RHVIPETNSRYSIFDVLRDELEVIL KAVLENSTAKDRPAVEKARTLYRSC MNQSVIEKRGSQPLLDILEVVGGWP VAMDRWNETVGLEWELERQLALMNS QFNRRVLIDLFIWNDDQNSSRHIIY IDQPTLGMPSREYYFNGGSNRKVRE AYLQFMVSVATLLREDANLPRDSCL VQEDMVQVLELETQLAKATVPQEER HDVIALYHRMGLEELQSQFGLKGFN WTLFIQTVLSSVKIKLLPDEEVVVY GIPYLQNLENIIDTYSARTIQNYLV WRLVLDRIGSLSQRFKDTRVNYRKA LFGTMVEEVRWRECVGYVNSNMENA VGSLYVREAFPGDSKSMVRELIDKV RTVFVETLDELGWIDEESKKKAQEK AMSIREQIGHPDYILEETNRRLDEE YSNLNFSEDLYFENSLQNLKVGAQR SLRKLREKVDPNLWIIGAAVVNAFY SPNRNQIVFPAGILQPPFFSKEQPQ ALNFGGIGMVIGHEITHGFDDNGRN FDKNGNMMDWWSNFSTQHFREQSEC MIYQYGNYSWDLADEQNVNGFNTLG ENIADNGGVRQAYKAYLKWMAEGGK DQQLPGLDLTHEQLFFINYAQVWCG SYRPEFAIQSIKTDVHSPLKYRVLG SLQNLAAFADTFHCARGTPMHPKER CRVW
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MMEL1 membrane metallo-endopeptidase-like 1 [ Homo sapiens ]
• Official Symbol: MMEL1
• Synonyms: MMEL1; membrane metallo-endopeptidase-like 1; membrane metallo endopeptidase like 2 , MMEL2; NEPII; NL1; NL2; SEP; NEP2(m); neprilysin-2; neprilysin II; zinc metallopeptidase; soluble secreted endopeptidase; membrane metallo-endopeptidase-like 2; NEP2; MMEL2; MGC119454; MGC119455; MGC119456
• Gene ID: 79258
• mRNA Refseq: NM_033467
• Protein Refseq: NP_258428
• UniProt ID: Q495T6