Recombinant Human MPP5 Protein, GST-tagged

• Cat.No.: MPP5-5513H
• Product Overview: Human MPP5 full-length ORF ( NP_071919.2, 1 a.a. - 675 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001 [PubMed 11311936]). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 103.7 kDa
• AA Sequence: MTTSHMNGHVTEESDSEVKNVDLAS PEEHQKHREMAVDCPGDLGTRMMPI RRSAQLERIRQQQEDMRRRREEEGK KQELDLNSSMRLKKLAQIPPKTGID NPMFDTEEGIVLESPHYAVKILEIE DLFSSLKHIQHTLVDSQSQEDISLL LQLVQNKDFQNAFKIHNAITVHMNK ASPPFPLISNAQDLAQEVQTVLKPV HHKEGQELTALLNTPHIQALLLAHD KVAEQEMQLEPITDERVYESIGQYG GETVKIVRIEKARDIPLGATVRNEM DSVIISRIVKGGAAEKSGLLHEGDE VLEINGIEIRGKDVNEVFDLLSDMH GTLTFVLIPSQQIKPPPAKETVIHV KAHFDYDPSDDPYVPCRELGLSFQK GDILHVISQEDPNWWQAYREGDEDN QPLAGLVPGKSFQQQREAMKQTIEE DKEPEKSGKLWCAKKNKKKRKKVLY NANKNDDYDNEEILTYEEMSLYHQP ANRKRPIILIGPQNCGQNELRQRLM NKEKDRFASAVPHTTRSRRDQEVAG RDYHFVSRQAFEADIAAGKFIEHGE FEKNLYGTSIDSVRQVINSGKICLL SLRTQSLKTLRNSDLKPYIIFIAPP SQERLRALLAKEGKNPKPEELREII EKTREMEQNNGHYFDTAIVNSDLDK AYQELLRLINKLDTEPQWVPSTWLR
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) [ Homo sapiens ]
• Official Symbol: MPP5
• Synonyms: MPP5; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); MAGUK p55 subfamily member 5; FLJ12615; PALS1; stardust; protein associated with lin seven 1
• Gene ID: 64398
• mRNA Refseq: NM_001256550
• Protein Refseq: NP_001243479
• MIM: 606958
• UniProt ID: Q8N3R9