Recombinant Human MPP6 Protein, GST-tagged

• Cat.No.: MPP6-5515H
• Product Overview: Human MPP6 full-length ORF ( AAH23638, 1 a.a. - 540 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.14 kDa
• AA Sequence: MQQVLENLTELPSSTGAEEIDLIFL KGIMENPIVKSLAKAHERLEDSKLE AVSDNNLELVNEILEDITPLINVDE NVAELVGILKEPHFQSLLEAHDIVA SKCYDSPPSSPEMNNSSINNQLLPV DAIRILGIHKRAGEPLGVTFRVENN DLVIARILHGGMIDRQGLLHVGDII KEVNGHEVGNNPKELQELLKNISGS VTLKILPSYRDTITPQQVFVKCHFD YNPYNDNLIPCKEAGLKFSKGEILQ IVNREDPNWWQASHVKEGGSAGLIP SQFLEEKRKAFVRRDWDNSGPFCGT ISSKKKKKMMYLTTRNAEFDRHEIQ IYEEVAKMPPFQRKTLVLIGAQGVG RRSLKNRFIVLNPTRFGTTVPFTSR KPREDEKDGQAYKFVSRSEMEADIK AGKYLEHGEYEGNLYGTKIDSILEV VQTGRTCILDVNPQALKVLRTSEFM PYVVFIAAPELETLRAMHKAVVDAG ITTKLLTDSDLKKTVDESARIQRAY NHYFDLIIINDNLDKAFEKLQTAIE KLRMEPQWVPISWVY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) [ Homo sapiens ]
• Official Symbol: MPP6
• Synonyms: MPP6; membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); MAGUK p55 subfamily member 6; p55T; PALS2; VAM 1; MAGUK protein p55T; VELI-associated MAGUK 1; protein associated with Lin7 2; VAM1; VAM-1
• Gene ID: 51678
• mRNA Refseq: NM_016447
• Protein Refseq: NP_057531
• MIM: 606959
• UniProt ID: Q9NZW5