Recombinant Human MRPL47 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : MRPL47-6443H
Product Overview : MRPL47 MS Standard C13 and N15-labeled recombinant protein (NP_817125) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 27.1 kDa
AA Sequence : MAAAGLALLCRRVSSALKSSRSLIT PQVPACTGLLHTTLSRKGLEEFFDD PKNWGQEKVKSGAAWTCQQLRNKSN EDLHKLWYVLLKERNMLLTLEQEAK RQRLPMPSPERLDKVVDSMDALDKV VQEREDALRLLQTGQERARPGAWRR DIFGRIIWHKFKQWVIPWHLNKRYN RKRFFALPYVDHFLRLEREKRARIK ARKENLERKKAKILLKKFPHLAEAQ KSSLVTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : MRPL47 mitochondrial ribosomal protein L47 [ Homo sapiens (human) ]
Official Symbol : MRPL47
Synonyms : MRPL47; mitochondrial ribosomal protein L47; NCM1; L47mt; CGI-204; MRP-L47; 39S ribosomal protein L47, mitochondrial; mitochondrial large ribosomal subunit protein uL29m; nasopharyngeal carcinoma metastasis-related 1; nasopharyngeal carcinoma metastasis-related protein 1
Gene ID : 57129
mRNA Refseq : NM_177988
Protein Refseq : NP_817125
MIM : 611852
UniProt ID : Q9HD33

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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