Recombinant Human MRPS31 Protein, His-tagged

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Recombinant Human MRPS31 Protein, His-tagged

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Cat.No. : MRPS31-1936H
Product Overview : Recombinant human MRPS31 protein, fused to His-tagged at N-terminus, was expressed in E. coli
Description : Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13. [provided by RefSeq, Jul 2008].
Source : E. coli
Species : Human
Tag : His
Form : 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 45.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : MRPS31 mitochondrial ribosomal protein S31 [ Homo sapiens ]
Official Symbol : MRPS31
Synonyms : IMOGN38; MRP-S31; S31mt
Gene ID : 10240
mRNA Refseq : NM_005830
Protein Refseq : NP_005821
MIM : 611992
UniProt ID : Q92665

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