Recombinant Human MSH3 HEK293T cell lysate


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Recombinant Human MSH3 HEK293T cell lysate

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Cat.No. : MSH3-23HCL
Product Overview : Human MSH3 was derived in Human HEK293T cell line.
Description : The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.
Source : HEK293
Species : Human
Tag : C-terminal Myc/DDK
Form : 1 vial of 100 µg gene specific transient over-expression cell lysate in RIPA buffer
1 vial of 100 µg empty vector transfected control cell lysate in RIPA buffer
1 vial of 250ul 2xSDS Sample Buffer (4% SDS, 125mM Tris-HCl pH6.8, 10% Glycerol, 0.002% Bromphenol blue, 100mM DTT)
Molecular Mass : 127.2 kDa
Storage : Upon receiving, store the sample at -20 centigrade. Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade. Avoid repeated freeze-thaw cycles.
Lysate samples can be diluted with 2xSDS Sample Buffer provided. After dilution, the protein sample should be aliquoted and stored at -20 centigrade for long term storage. Prior to SDS-PAGE fractionation, boil the lysate for 5 minutes.
Gene Name : MSH3 mutS homolog 3 (E. coli) [ Homo sapiens ]
Official Symbol : MSH3
Synonyms : MSH3; mutS homolog 3 (E. coli); mutS (E. coli) homolog 3; DNA mismatch repair protein Msh3; Divergent upstream protein; DUP; Mismatch repair protein 1; MRP1; hMSH3; mismatch repair protein 1; divergent upstream protein; MGC163306; MGC163308;
Gene ID : 4437
mRNA Refseq : NM_002439
Protein Refseq : NP_002430
MIM : 600887
UniProt ID : P20585
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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