Recombinant Human MTHFD1 Protein, GST-tagged
Cat.No. : | MTHFD1-5702H |
Product Overview : | Human MTHFD1 full-length ORF ( AAH09806, 1 a.a. - 935 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 128.59 kDa |
AA Sequence : | MAPAEILNGKEISAQIRARLKNQVT QLKEQVPGFTPRLAILQVGNRDDSN LYINVKLKAAEEIGIKATHIKLPRT TTESEVMKYITSLNEDSTVHGFLVQ LPLDSENSINTEEVINAIAPEKDVD GLTSINAGRLARGDLNDCFIPCTPK GCLELIKETGVPIAGRHAVVVGRSK IVGAPMHDLLLWNNATVTTCHSKTA HLDEEVNKGDILVVATGQPEMVKGE WIKPGAIVIDCGINYVPDDKKPNGR KVVGDVAYDEAKERASFITPVPGGV GPMTVAMLMQSTVESAKRFLEKFKP GKWMIQYNNLNLKTPVPSDIDISRS CKPKPIGKLAREIGLLSEEVELYGE TKAKVLLSALERLKHRPDGKYVVVT GITPTPLGEGKSTTTIGLVQALGAH LYQNVFACVRQPSQGPTFGIKGGAA GGGYSQVIPMEEFNLHLTGDIHAIT AANNLVAAAIDARIFHELTQTDKAL FNRLVPSVNGVRRFSDIQIRRLKRL GIEKTDPTTLTDEEINRFARLDIDP ETITWQRVLDTNDRFLRKITIGQAP TEKGHTRTAQFDISVASEIMAVLAL TTSLEDMRERLGKMVVASSKKGEPV SAEDLGVSGALTVLMKDAIKPNLMQ TLEGTPVFVHAGPFANIAHGNSSII ADQIALKLVGPEGFVVTEAGFGADI GMEKFFNIKCRYSGLCPHVVVLVAT VRALKMHGGGPTVTAGLPLPKAYIQ ENLELVEKGFSNLKKQIENARMFGI PVVVAVNAFKTDTESELDLISRLSR EHGAFDAVKCTHWAEGGKGALALAQ AVQRAAQAPSSFQLLYDLKLPVEDK IRIIAQKIYGADDIELLPEAQHKAE VYTKQGFGNLPICMAKTHLSLSHNP EQKGVPTGFILPIRDIRASVGAGFL YPLVGTMSTMPGLPTRPCFYDIDLD PETEQVNGLF |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase [ Homo sapiens ] |
Official Symbol : | MTHFD1 |
Synonyms : | MTHFD1; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase; MTHFC, MTHFD; C-1-tetrahydrofolate synthase, cytoplasmic; C1-THF synthase; cytoplasmic C-1-tetrahydrofolate synthase; 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase; MTHFC; MTHFD; |
Gene ID : | 4522 |
mRNA Refseq : | NM_005956 |
Protein Refseq : | NP_005947 |
MIM : | 172460 |
UniProt ID : | P11586 |
Products Types
◆ Recombinant Protein | ||
MTHFD1-1452H | Recombinant Human MTHFD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MTHFD1-2185H | Recombinant Human MTHFD1 Protein, MYC/DDK-tagged | +Inquiry |
MTHFD1-1869P | Recombinant Pongo Abelii MTHFD1 Protein (1-305 aa), His-SUMO-tagged | +Inquiry |
Mthfd1-370M | Recombinant Mouse Mthfd1 Protein, MYC/DDK-tagged | +Inquiry |
MTHFD1-3468R | Recombinant Rat MTHFD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
MTHFD1-1146HCL | Recombinant Human MTHFD1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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