Recombinant Human MTMR14 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MTMR14-599H
• Product Overview: MTMR14 MS Standard C13 and N15-labeled recombinant protein (NP_001070994) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 66.7 kDa
• AA Sequence: MAGARAAAAAASAGSSASSGNQPPQ ELGLGELLEEFSRTQYRAKDGSGTG GSKVERIEKRCLELFGRDYCFSVIP NTNGDICGHYPRHIVFLEYESSEKE KDTFESTVQVSKLQDLIHRSKMARC RGRFVCPVILFKGKHICRSATLAGW GELYGRSGYNYFFSGGADDAWADVE DVTEEDCALRSGDTHLFDKVRGYDI KLLRYLSVKYICDLMVENKKVKFGM NVTSSEKVDKAQRYADFTLLSIPYP GCEFFKEYKDRDYMAEGLIFNWKQD YVDAPLSIPDFLTHSLNIDWSQYQC WDLVQQTQNYLKLLLSLVNSDDDSG LLVHCISGWDRTPLFISLLRLSLWA DGLIHTSLKPTEILYLTVAYDWFLF GHMLVDRLSKGEEIFFFCFNFLKHI TSEEFSALKTQRRKSLPARDGGFTL EDICMLRRKDRGSTTSLGSDFSLVM ESSPGATGSFTYEAVELVPAGAPTQ AAWRKSHSSSPQSVLWNRPQPSEDR LPSQQGLAEARSSSSSSSNHSDNFF RMGSSPLEVPKPRLAALSDRETRLQ EVRSAFLAAYSSTVGLRAVAPSPSG AIGGLLEQFARGVGLRSISSNALTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MTMR14 myotubularin related protein 14 [ Homo sapiens (human) ]
• Official Symbol: MTMR14
• Synonyms: MTMR14; myotubularin related protein 14; C3orf29, chromosome 3 open reading frame 29; myotubularin-related protein 14; egg derived tyrosine phosphatase homolog (Drosophila); FLJ22405; FLJ90311; hEDTP; hJumpy; jumpy; NS5ATP4ABP1; egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1; C3orf29; FLJ11546; FLJ46453
• Gene ID: 64419
• mRNA Refseq: NM_001077526
• Protein Refseq: NP_001070994
• MIM: 611089
• UniProt ID: Q8NCE2