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Recombinant Human MUTYH Protein, GST-tagged

Cat.No. : MUTYH-5765H
Product Overview : Human MUTYH full-length ORF ( NP_001041636.1, 1 a.a. - 535 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 85.5 kDa
AA Sequence : MTPLVSRLSRLWAIMRKPRAAVGSG HRKQAASQEGRQKHAKNNSQAKPSA CDGLARQPEEVVLQASVSSYHLFRD VAEVTAFRGSLLSWYDQEKRDLPWR RRAEDEMDLDRRAYAVWVSEVMLQQ TQVATVINYYTGWMQKWPTLQDLAS ASLEEVNQLWAGLGYYSRGRRLQEG ARKVVEELGGHMPRTAETLQQLLPG VGRYTAGAIASIAFGQATGVVDGNV ARVLCRVRAIGADPSSTLVSQQLWG LAQQLVDPARPGDFNQAAMELGATV CTPQRPLCSQCPVESLCRARQRVEQ EQLLASGSLSGSPDVEECAPNTGQC HLCLPPSEPWDQTLGVVNFPRKASR KPPREESSATCVLEQPGALGAQILL VQRPNSGLLAGLWEFPSVTWEPSEQ LQRKALLQELQRWAGPLPATHLRHL GEVVHTFSHIKLTYQVYGLALEGQT PVTTVPPGARWLTQEEFHTAAVSTA MKKVFRVYQGQQPGTCMGSKRSQVS SPCSRKKPRMGQQVLDNFFRSHIST DAHSLNSAAQ
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MUTYH mutY homolog (E. coli) [ Homo sapiens ]
Official Symbol : MUTYH
Synonyms : MUTYH; mutY homolog (E. coli); mutY (E. coli) homolog; A/G-specific adenine DNA glycosylase; MYH; CYP2C; MGC4416;
Gene ID : 4595
mRNA Refseq : NM_001048171
Protein Refseq : NP_001041636
MIM : 604933
UniProt ID : Q9UIF7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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