Recombinant Human MYLIP Protein (1-445 aa), His-tagged
Cat.No. : | MYLIP-1703H |
Product Overview : | Recombinant Human MYLIP Protein (1-445 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Epigenetics and Nuclear Signaling. Protein Description: Full Length. |
- Specification
- Gene Information
- Related Products
Description : | E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 51.9 kDa |
Protein length : | 1-445 aa |
AA Sequence : | MLCYVTRPDAVLMEVEVEAKANGED CLNQVCRRLGIIEVDYFGLQFTGSK GESLWLNLRNRISQQMDGLAPYRLK LRVKFFVEPHLILQEQTRHIFFLHI KEALLAGHLLCSPEQAVELSALLAQ TKFGDYNQNTAKYNYEELCAKELSS ATLNSIVAKHKELEGTSQASAEYQV LQIVSAMENYGIEWHSVRDSEGQKL LIGVGPEGISICKDDFSPINRIAYP VVQMATQSGKNVYLTVTKESGNSIV LLFKMISTRAASGLYRAITETHAFY RCDTVTSAVMMQYSRDLKGHLASLF LNENINLGKKYVFDIKRTSKEVYDH ARRALYNAGVVDLVSRNNQSPSHSP LKSSESSMNCSSCEGLSCQQTRVLQ EKLRKLKEAMLCMVCCEEEINSTFC PCGHTVCCESCAAQLQSCPVCRSRV EHVQHVYLPTHTSLLNLTVI |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | MYLIP myosin regulatory light chain interacting protein [ Homo sapiens ] |
Official Symbol : | MYLIP |
Synonyms : | MYLIP; IDOL; MIR; band 4.1 superfamily member BZF1; |
Gene ID : | 29116 |
mRNA Refseq : | NM_013262 |
Protein Refseq : | NP_037394 |
MIM : | 610082 |
UniProt ID : | Q8WY64 |
Products Types
◆ Recombinant Protein | ||
MYLIP-2744R | Recombinant Rhesus Macaque MYLIP Protein, His (Fc)-Avi-tagged | +Inquiry |
MYLIP-1103H | Recombinant Human MYLIP Protein (1-445 aa), GST-tagged | +Inquiry |
MYLIP-5849M | Recombinant Mouse MYLIP Protein, His (Fc)-Avi-tagged | +Inquiry |
MYLIP-5819H | Recombinant Human MYLIP Protein, GST-tagged | +Inquiry |
MYLIP-1933C | Recombinant Chicken MYLIP | +Inquiry |
◆ Lysates | ||
MYLIP-4018HCL | Recombinant Human MYLIP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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