Recombinant Human MYO1G Protein (Gly769-Pro1016), His tagged

Species :	Human
Source :	E.coli
Tag :	His
Protein Length :	Gly769-Pro1016
Description :	Unconventional myosin required during immune response for detection of rare antigen-presenting cells by regulating T-cell migration. Unconventional myosins are actin-based motor molecules with ATPase activity and serve in intracellular movements. Acts as a regulator of T-cell migration by generating membrane tension, enforcing cell-intrinsic meandering search, thereby enhancing detection of rare antigens during lymph-node surveillance, enabling pathogen eradication. Also required in B-cells, where it regulates different membrane/cytoskeleton-dependent processes. Involved in Fc-gamma receptor (Fc-gamma-R) phagocytosis.
Molecular Mass :	29.59 kDa
Purity :	>90 % as determined by SDS-PAGE.
Notes :	For research use only.
Storage :	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer :	Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
Reconstitution :	Reconstitute in sterile water for a stock solution.
Shipping :	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Name	MYO1G myosin IG [ Homo sapiens (human) ]
Official Symbol	MYO1G
Synonyms	HA2; MHAG
Gene ID	64005
mRNA Refseq	NM_033054
Protein Refseq	NP_149043
MIM	613445
UniProt ID	B0I1T2