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Recombinant Human MYOT Protein, GST-tagged

Cat.No. : MYOT-5856H
Product Overview : Human MYOT full-length ORF ( NP_006781.1, 1 a.a. - 498 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 81.8 kDa
AA Sequence : MFNYERPKHFIQSQNPCGSRLQPPG PETSSFSSQTKQSSIIIQPRQCTEQ RFSASSTLSSHITMSSSAFPASPQQ HAGSNPGQRVTTTYNQSPASFLSSI LPSQPDYNSSKIPSAMDSNYQQSSA GQPINAKPSQTANAKPIPRTPDHEI QGSKEALIQDLERKLKCKDTLLHNG NQRLTYEEKMARRLLGPQNAAAVFQ AQDDSGAQDSQQHNSEHARLQVPTS QVRSRSTSRGDVNDQDAIQEKFYPP RFIQVPENMSIDEGRFCRMDFKVSG LPAPDVSWYLNGRTVQSDDLHKMIV SEKGLHSLIFEVVRASDAGAYACVA KNRAGEATFTVQLDVLAKEHKRAPM FIYKPQSKKVLEGDSVKLECQISAI PPPKLFWKRNNEMVQFNTDRISLYQ DNTGRVTLLIKDVNKKDAGWYTVSA VNEAGVTTCNTRLDVTARPNQTLPA PKQLRVRPTFSKYLALNGKGLNVKQ AFNPEGEFQRLAAQSGLYESEEL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : MYOT myotilin [ Homo sapiens ]
Official Symbol : MYOT
Synonyms : MYOT; myotilin; LGMD1, LGMD1A, limb girdle muscular dystrophy 1A (autosomal dominant) , titin immunoglobulin domain protein (myotilin) , TTID; 57 kDa cytoskeletal protein; myofibrillar titin-like Ig domains protein; titin immunoglobulin domain protein (myotilin); TTID; LGMD1; LGMD1A;
Gene ID : 9499
mRNA Refseq : NM_001135940
Protein Refseq : NP_001129412
MIM : 604103
UniProt ID : Q9UBF9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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