Recombinant Human N-methylpurine-DNA glycosylase Protein, His tagged

• Cat.No.: MPG-160H
• Product Overview: Recombinant human MPG protein (P29372-1) (Met 18-Ala 298) with a His tag at the C-terminus was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 18-298aa
• Description: Predicted to enable alkylbase DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Located in cytosol and nucleoplasm. Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
• Tag: C-His
• Molecular Mass: 32.5 kDa
• Endotoxin: Less than 1.0 EU/μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: Please avoid repeated freeze-thaw cycles. Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade. It is recommended that aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4, 5% Trehalose, 5% mannitol.
• Reconstitution: Reconstitute at 250 μg/mL in sterile water.

Gene Information

• Gene Name: MPG N-methylpurine-DNA glycosylase [ Homo sapiens (human) ]
• Official Symbol: MPG
• Synonyms: MPG; N-methylpurine-DNA glycosylase; DNA-3-methyladenine glycosylase; alkyladenine DNA glycosylase; MDG; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; proliferation-inducing protein 11; proliferation-inducing protein 16; N-methylpurine-DNA glycosylase, MPG; CRA36.1 (3-methyl-adenine DNA glycosylase); 3 end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; AAG; ADPG; APNG; Mid1; anpg; PIG11; PIG16; CRA36.1
• Gene ID: 4350
• mRNA Refseq: NM_001015052
• Protein Refseq: NP_001015052
• MIM: 156565
• UniProt ID: P29372