Recombinant Human NAE1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | NAE1-4720H |
Product Overview : | NAE1 MS Standard C13 and N15-labeled recombinant protein (NP_001018170) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 60.2 kDa |
AA Sequence : | MAQLGKLLKEQKYDRQLRLWGDHGQ EALESAHVCLINATATGTEILKNLV LPGIGSFTIIDGNQVSGEDAGNNFF LQRSSIGKNRAEAAMEFLQELNSDV SGSFVEESPENLLDNDPSFFCRFTV VVATQLPESTSLRLADVLWNSQIPL LICRTYGLVGYMRIIIKEHPVIESH PDNALEDLRLDKPFPELREHFQSYD LDHMEKKDHSHTPWIVIIAKYLAQW YSETNGRIPKTYKEKEDFRDLIRQG ILKNENGAPEDEENFEEAIKNVNTA LNTTQIPSSIEDIFNDDRCINITKQ TPSFWILARALKEFVAKEGQGNLPV RGTIPDMIADSGKYIKLQNVYREKA KKDAAAVGNHVAKLLQSIGQAPESI SEKELKLLCSNSAFLRVVRCRSLAE EYGLDTINKDEIISSMDNPDNEIVL YLMLRAVDRFHKQQGRYPGVSNYQV EEDIGKLKSCLTGFLQEYGLSVMVK DDYVHEFCRYGAAEPHTIAAFLGGA AAQEVIKIITKQFVIFNNTYIYSGM SQTSATFQLTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | NAE1 NEDD8 activating enzyme E1 subunit 1 [ Homo sapiens (human) ] |
Official Symbol : | NAE1 |
Synonyms : | NAE1; NEDD8 activating enzyme E1 subunit 1; amyloid beta precursor protein binding protein 1, amyloid beta precursor protein binding protein 1, 59kDa, amyloid beta precursor protein binding protein 1, 59kD, APPBP1; NEDD8-activating enzyme E1 regulatory subunit; NEDD8 activating enzyme E1 subunit; ula 1; APP-BP1; protooncogene protein 1; proto-oncogene protein 1; amyloid protein-binding protein 1; NEDD8-activating enzyme E1 subunit; amyloid beta precursor protein-binding protein 1, 59kD; amyloid beta precursor protein binding protein 1, 59kDa; amyloid beta precursor protein-binding protein 1, 59 kDa; HPP1; ula-1; APPBP1; A-116A10.1; |
Gene ID : | 8883 |
mRNA Refseq : | NM_001018160 |
Protein Refseq : | NP_001018170 |
MIM : | 603385 |
UniProt ID : | Q13564 |
Products Types
◆ Recombinant Protein | ||
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NAE1-2761R | Recombinant Rhesus Macaque NAE1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NAE1-32H | Recombinant Human NAE1 Protein, His-tagged | +Inquiry |
NAE1-417H | Recombinant Human NAE1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NAE1-3984HCL | Recombinant Human NAE1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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