| Description : |
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
268.6 kDa |
| AA Sequence : |
MAAPESGPALSPGTAEGEEETILYD LLVNTEWPPETEVQPRGNQKHGASF IITKAIRDRLLFLRQYIWYSPAPFL LPDGLVRLVNKQINWHLVLASNGKL LAAVQDQCVEIRSAKDDFTSIIGKC QVPKDPKPQWRRVAWSYDCTLLAYA ESTGTVRVFDLMGSELFVISPASSF IGDLSYAIAGLIFLEYKASAQWSAE LLVINYRGELRSYLVSVGTNQSYQE SHCFSFSSHYPHGINTAVYHPGHRL LLVGGCETAEVGMSKASSCGLSAWR VLSGSPYYKQVTNGGDGVTAVPKTL GLLRMLSVKFYSRQGQEQDGIFKMS LSPDGMLLAAIHFSGKLSIWAIPSL KQQGEWGQNEQPGYDDLNPDWRLST EKRKKIKDKESFYPLIDVNWWADSA VTLARCSGALTVSSVKTLKNLLGKS CEWFEPSPQVTATHDGGFLSLECEI KLAPKRSRLETRAGEEDEGEEDSDS DYEISAKARYFGYIKQGLYLVTEME RFAPPRKRPRTITKNYRLVSLRSTT PEELYQRKIESEEYEEALSLAHTYG LDTDLVYQRQWRKSAVNVASIQNYL SKIKKRSWVLHECLERVPENVDAAK ELLQYGLKGTDLEALLAIGKGADDG RFTLPGEIDIDSISYEELSPPDEEP AKNKREKELKKRQELLKLVNFSKLT LEQKELCRCRRKLLTYLDRLATYEE ILGVPHASEQRYDAEFFKKFRNQNI VLSARTYAQESNVQALEILFTYHGS DLLPHRLAILSNFPETTSPHEYSVL LPEACFNGDSLMIIPWHEHKHRAKD WCEELACRMVVEPNLQDESEFLYAA QPELLRFRMTQLTVEKVMDWYQTRA EEIEHYARQVDCALSLIRLGMERNI PGLLVLCDNLVTLETLVYEARCDVT LTLKELQQMKDIEKLRLLMNSCSED KYVTSAYQWMVPFLHRCEKQSPGVA NELLKEYLVTLAKGDLKFPLKIFQH SKPDLQQKIIPDQDQLMAIALECIY TCERNDQLCLCYDLLECLPERGYGD KTEATTKLHDMVDQLEQILSVSELL EKHGLEKPISFVKNTQSSSEEARKL MVRLTRHTGRKQPPVSESHWRTLLQ DMLTMQQNVYTCLDSDACYEIFTES LLCSSRLENIHLAGQMMHCSACSEN PPAGIAHKGKPHYRVSYEKSIDLVL AASREYFNSSTNLTDSCMDLARCCL QLITDRPPAIQEELDLIQAVGCLEE FGVKILPLQVRLCPDRISLIKECIS QSPTCYKQSTKLLGLAELLRVAGEN PEERRGQVLILLVEQALRFHDYKAA SMHCQELMATGYPKSWDVCSQLGQS EGYQDLATRQELMAFALTHCPPSSI ELLLAASSSLQTEILYQRVNFQIHH EGGENISASPLTSKAVQEDEVGVPG SNSADLLRWTTATTMKVLSNTTTTT KAVLQAVSDGQWWKKSLTYLRPLQG QKCGGAYQIGTTANEDLEKQGCHPF YESVISNPFVAESEGTYDTYQHVPV ESFAEVLLRTGKLAEAKNKGEVFPT TEVLLQLASEALPNDMTLALAYLLA LPQVLDANRCFEKQSPSALSLQLAA YYYSLQIYARLAPCFRDKCHPLYRA DPKELIKMVTRHVTRHEHEAWPEDL ISLTKQLHCYNERLLDFTQAQILQG LRKGVDVQRFTADDQYKRETILGLA ETLEESVYSIAISLAQRYSVSRWEV FMTHLEFLFTDSGLSTLEIENRAQD LHLFETLKTDPEAFHQHMVKYIYPT IGGFDHERLQYYFTLLENCGCADLG NCAIKPETHIRLLKKFKVVASGLNY KKLTDENMSPLEALEPVLSSQNILS ISKLVPKIPEKDGQMLSPSSLYTIW LQKLFWTGDPHLIKQVPGSSPEWLH AYDVCMKYFDRLHPGDLITVVDAVT FSPKAVTKLSVEARKEMTRKAIKTV KHFIEKPRKRNSEDEAQEAKDSKVT YADTLNHLEKSLAHLETLSHSFILS LKNSEQETLQKYSHLYDLSRSEKEK LHDEAVAICLDGQPLAMIQQLLEVA VGPLDISPKDIVQSAIMKIISALSG GSADLGGPRDPLKVLEGVVAAVHAS VDKGEELVSPEDLLEWLRPFCADDA WPVRPRIHVLQILGQSFHLTEEDSK LLVFFRTEAILKASWPQRQVDIADI ENEENRYCLFMELLESSHHEAEFQH LVLLLQAWPPMKSEYVITNNPWVRL ATVMLTRCTMENKEGLGNEVLKMCR SLYNTKQMLPAEGVKELCLLLLNQS LLLPSLKLLLESRDEHLHEMALEQI TAVTTVNDSNCDQELLSLLLDAKLL VKCVSTPFYPRIVDHLLASLQQGRW DAEELGRHLREAGHEAEAGSLLLAV RGTHQAFRTFSTALRAAQHWVTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
