Species : |
Human |
Source : |
E.coli |
Tag : |
His |
Protein Length : |
Met1-Arg218 |
Description : |
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Form : |
Freeze-dried powder |
Molecular Mass : |
Predicted Molecular Mass: 25.2 kDa |
Endotoxin : |
<1.0 EU per 1µg (determined by the LAL method). |
Purity : |
> 95% |
Applications : |
Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : |
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : |
Reconstitute in PBS or others. |