Recombinant Human NBN Protein, His-tagged
Cat.No. : | NBN-2480H |
Product Overview : | Recombinant Human NBN Protein (Met1-Arg218) with a N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 25.2 kDa |
Protein length : | Met1-Arg218 |
Endotoxin : | <1.0 EU per 1µg (determined by the LAL method). |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | NBN nibrin [ Homo sapiens (human) ] |
Official Symbol : | NBN |
Synonyms : | NBN; nibrin; NBS, NBS1, Nijmegen breakage syndrome 1 (nibrin); AT V1; AT V2; ATV; cell cycle regulatory protein p95; Nijmegen breakage syndrome 1 (nibrin); p95 protein of the MRE11/RAD50 complex; NBS; P95; NBS1; AT-V1; AT-V2; FLJ10155; MGC87362; |
Gene ID : | 4683 |
mRNA Refseq : | NM_002485 |
Protein Refseq : | NP_002476 |
MIM : | 602667 |
UniProt ID : | O60934 |
Products Types
◆ Recombinant Protein | ||
NBN-01H | Recombinant Human NBN Protein, His-tagged | +Inquiry |
NBN-001H | Recombinant Human NBN Protein, His-tagged | +Inquiry |
NBN-2479H | Recombinant Human NBN Protein, His-tagged | +Inquiry |
NBN-3571R | Recombinant Rat NBN Protein, His (Fc)-Avi-tagged | +Inquiry |
NBN-2771R | Recombinant Rhesus Macaque NBN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NBN-3957HCL | Recombinant Human NBN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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