Recombinant Human NDUFB4, His-tagged

• Cat.No.: NDUFB4-7585H
• Product Overview: Recombinant human NDUFB4 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-87aa
• Antigen Description: NDUFB4 is a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first enzyme complex in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to ubiquinone.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 12.6 kDa (110aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSFPKYK PSSLRTLPET LDPAEYNISP ETRRAQAERL AIRAQLKREY LLQYNDPNRR GLIENPALLR WAYARTINVY PNFRPTPKNS
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: NDUFB4?NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa [?Homo sapiens?]
• Official Symbol: NDUFB4
• Synonyms: NDUFB4; B15; CI-B15; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4; complex I-B15; complex I B15 subunit; NADH-ubiquinone oxidoreductase B15 subunit; 15kDa; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4 (15kD, B15); NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
• Gene ID: 4710
• mRNA Refseq: NM_001168331
• Protein Refseq: NP_001161803
• MIM: 603840
• UniProt ID: O95168
• Chromosome Location: 3q13.33
• Pathway: Alzheimer"s disease; Electron Transport Chain; Huntington"s disease; Metabolism
• Function: NADH dehydrogenase (ubiquinone) activity