Recombinant Human NECTIN4 Protein (Ala31-Val317), N-His tagged

• Cat.No.: NECTIN4-3794H
• Product Overview: Recombinant human NECTIN4 (Ala31-Val317) fused with the N-His tag was expressed in E. coli.

Specification

• Description: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 33.07 kDa
• Protein Length: Ala31-Val317
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: NECTIN4 nectin cell adhesion molecule 4 [ Homo sapiens (human) ]
• Official Symbol: NECTIN4
• Synonyms: NECTIN4; nectin cell adhesion molecule 4; LNIR; PRR4; EDSS1; PVRL4; nectin-4; nectin-4; Ig superfamily receptor LNIR; nectin 4; poliovirus receptor-related 4; poliovirus receptor-related protein 4
• Gene ID: 81607
• mRNA Refseq: NM_030916
• Protein Refseq: NP_112178
• MIM: 609607
• UniProt ID: Q96NY8