Recombinant Human NECTIN4 Protein, His-tagged

• Cat.No.: NECTIN4-154H
• Product Overview: Recombinant Human nectin cell adhesion molecule 4(NECTIN4)(NM_030916) protein, with a His tag, was expressed in human cells.

Specification

• Description: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
• Source: Human Cells
• Species: Human
• Tag: His
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.383, without any preservatives.
• Molecular Mass: 55.3 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: NECTIN4 nectin cell adhesion molecule 4 [ Homo sapiens (human) ]
• Official Symbol: NECTIN4
• Synonyms: EDSS1; Ig superfamily receptor LNIR; LNIR; LNIRnectin 4; Nectin4; Nectin-4; poliovirus receptor-related 4; poliovirus receptor-related protein 4; PRR4; PRR4DKFZp686K05193; PVRL4
• Gene ID: 81607
• mRNA Refseq: NM_030916
• Protein Refseq: NP_112178
• MIM: 609607
• UniProt ID: Q96NY8