| Description : |
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
92.9 kDa |
| AA Sequence : |
MKYKNLMARALYDNVPECAEELAFR KGDILTVIEQNTGGLEGWWLCSLHG RQGIVPGNRVKLLIGPMQETASSHE QPASGLMQQTFGQQKLYQVPNPQAA PRDTIYQVPPSYQNQGIYQVPTGHG TQEQEVYQVPPSVQRSIGGTSGPHV GKKVITPVRTGHGYVYEYPSRYQKD VYDIPPSHTTQGVYDIPPSSAKGPV FSVPVGEIKPQGVYDIPPTKGVYAI PPSACRDEAGLREKDYDFPPPMRQA GRPDLRPEGVYDIPPTCTKPAGKDL HVKYNCDIPGAAEPVARRHQSLSPN HPPPQLGQSVGSQNDAYDVPRGVQF LEPPAETSEKANPQERDGVYDVPLH NPPDAKGSRDLVDGINRLSFSSTGS TRSNMSTSSTSSKESSLSASPAQDK RLFLDPDTAIERLQRLQQALEMGVS SLMALVTTDWRCYGYMERHINEIRT AVDKVELFLKEYLHFVKGAVANAAC LPELILHNKMKRELQRVEDSHQILS QTSHDLNECSWSLNILAINKPQNKC DDLDRFVMVAKTVPDDAKQLTTTIN TNAEALFRPGPGSLHLKNGPESIMN STEYPHGGSQGQLLHPGDHKAQAHN KALPPGLSKEQAPDCSSSDGSERSW MDDYDYVHLQGKEEFERQQKELLEK ENIMKQNKMQLEHHQLSQFQLLEQE ITKPVENDISKWKPSQSLPTTNSGV SAQDRQLLCFYYDQCETHFISLLNA IDALFSCVSSAQPPRIFVAHSKFVI LSAHKLVFIGDTLTRQVTAQDIRNK VMNSSNQLCEQLKTIVMATKMAALH YPSTTALQEMVHQVTDLSRNAQLFK RSLLEMATFTRTRPLEQKLISEEDL AANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
