Recombinant Human NELL1, His-tagged

• Cat.No.: NELL1-106H
• Product Overview: Recombinant Human Protein Kinase C-Binding Protein NELL1/NELL1 is produced in mammalian expression system in human cells. The target protein is expressed with sequence (Arg17-Asn810) of Human NELL1 fused with a 6His tag at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: 17-810 a.a.
• Description: This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Alternative splicing results in multiple transcript variants.
• Form: Supplied as a 0.2 uM filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
• AA Sequence: RTVVGFGMDPDLQMDIVTELDLVNTTLGVAQVSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLF QNKSEFTILATVQQKPSTSGVILSIRELEHSYFELESSGLRDEIRYHYIHNGKPRTEALPYRMAD GQWHKVALSVSASHLLLHVDCNRIYERVIDPPDTNLPPGINLWLGQRNQKHGLFKGIIQDGKIIF MPNGYITQCPNLNHTCPTCSDFLSLVQGIMDLQELLAKMTAKLNYAETRLSQLENCHCEKTCQVS GLLYRDQDSWVDGDHCRNCTCKSGAVECRRMSCPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKV LAEGQRILTKSCRECRGGVLVKITEMCPPLNCSEKDHILPENQCCRVCRGHNFCAEGPKCGENSE CKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLYRCDCVPGYIRVDD FSCTEHDECGSGQHNCDENAICTNTVQGHSCTCKPGYVGNGTICRAFCEEGCRYGGTCVAPNKCV CPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCIDIDECA LRTHTCWNDSACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFC RRTACDCQNPSADLFCCPECDTRVTSQCLDQNGHKLYRSGDNWTHSCQQCRCLEGEVDCWPLTCP NLSCEYTAILEGECCPRCVSDPCLADNITYDIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNG RVCCSVDFECLQNNLDHHHHHH
• Endotoxin: Less than 0.1 ng/µg (1 IEU/µg).
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Storage: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Gene Information

• Gene Name: NELL1 NEL-like 1 (chicken) [ Homo sapiens (human) ]
• Official Symbol: NELL1
• Synonyms: NELL1; NRP1; IDH3GL; NEL-like 1 (chicken); protein kinase C-binding protein NELL1; nel-related protein 1; neural epidermal growth factor-like 1
• Gene ID: 4745
• mRNA Refseq: NM_006157
• Protein Refseq: NP_006148
• MIM: 602319
• UniProt ID: Q92832
• Chromosome Location: 11p15.1
• Function: calcium ion binding; protein binding