Recombinant Human NES Protein (1321-1569 aa), His-tagged

• Cat.No.: NES-1473H
• Product Overview: Recombinant Human NES Protein (1321-1569 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial.

Specification

• Description: Required for brain and eye development. Promotes the disassbly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 27.8 kDa
• Protein length: 1321-1569 aa
• AA Sequence: PPPQGETGKEGWDPAVLASEGLEAP PSEKEEGEEGEEECGRDSDLSEEFE DLGTEAPFLPGVPGEVAEPLGQVPQ LLLDPAAWDRDGESDGFADEEESGE EGEEDQEEGREPGAGRWGPGSSVGS LQALSSSQRGEFLESDSVSVSVPWD DSLRGAVAGAPKTALETESQDSAEP SGSEEESDPVSLEREDKVPGPLEIP SGMEDAGPGADIIGVNGQGPNLEGK SQHVNGGVMNGLEQSEEVGQGMPL
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: NES nestin [ Homo sapiens ]
• Official Symbol: NES
• Synonyms: NES; nestin; FLJ21841; Nbla00170
• Gene ID: 10763
• mRNA Refseq: NM_006617
• Protein Refseq: NP_006608
• MIM: 600915
• UniProt ID: P48681