Recombinant Human NFYC Protein, His/GST-tagged

• Cat.No.: NFYC-308H
• Product Overview: Recombinant Human NFYC(Met1~Val263) fused with His/GST tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His/GST
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 59.3kDa
• Protein length: Met1~Val263
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NFYC nuclear transcription factor Y, gamma [ Homo sapiens ]
• Official Symbol: NFYC
• Synonyms: NFYC; nuclear transcription factor Y, gamma; nuclear transcription factor Y subunit gamma; CBF C; NF YC; transactivator HSM-1; transactivator HSM-1/2; CCAAT binding factor subunit C; transcription factor NF-Y, C subunit; CAAT box DNA-binding protein subunit C; nuclear transcription factor Y subunit C; CCAAT transcription binding factor subunit gamma; histone H1 transcription factor large subunit 2A; HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A; FLJ45775; DKFZp667G242
• Gene ID: 4802
• mRNA Refseq: NM_001142587
• Protein Refseq: NP_001136059
• MIM: 605344
• UniProt ID: Q13952