Recombinant Human NLGN4X protein, His-tagged

• Cat.No.: NLGN4X-712H
• Product Overview: Recombinant Human NLGN4X (Gln42-Ser676) protein was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293).

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Gln42-Ser676
• Description: Neuroligin-4, X-linked (NLGN4X) is also known as HNLX, KIAA1260, NLGN4, ASPGX2, AUTSX2, HLNX, HNL4X, NLGN, NLGN4, which belongs to the type-B carboxylesterase/lipase family, a neuronal cell surface proteins. NLGN4X is a homodimer, which can interacts with NRXN1 in a calcium-dependent manner and also interacts through its C-terminus with DLG4/PSD-95 third PDZ domain. Neuroligins may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. NLGN4X is putative neuronal cell surface protein involved in cell-cell-interactions.
• Predicted N Terminal: Gln42
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 72.2 kDa. The protein migrates as 80-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20 to -70 centigrade for 12 months in lyophilized state;
  -70 centigrade for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: NLGN4X
• Official Symbol: NLGN4X
• Synonyms: NLGN4X; neuroligin 4, X-linked; neuroligin 4, NLGN4; neuroligin-4, X-linked; HLNX; KIAA1260; NLGN; neuroligin X; HNLX; HNL4X; NLGN4; ASPGX2; AUTSX2; MGC22376
• Gene ID: 57502
• mRNA Refseq: NM_020742
• Protein Refseq: NP_065793
• MIM: 300427
• UniProt ID: Q8N0W4