Recombinant Human NONO protein, MYC/DDK-tagged
Cat.No. : | NONO-852H |
Product Overview : | Recombinant Human NONO, transcript variant 1, fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 54.1 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | NONO non-POU domain containing, octamer-binding [ Homo sapiens ] |
Official Symbol : | NONO |
Synonyms : | NONO; non-POU domain containing, octamer-binding; non POU domain containing, octamer binding; non-POU domain-containing octamer-binding protein; NMT55; non Pou domain containing octamer (ATGCAAAT) binding protein; NRB54; Nuclear RNA binding protein; 54 kD; P54; P54NRB; p54(nrb); 55 kDa nuclear protein; 54 kDa nuclear RNA- and DNA-binding protein; DNA-binding p52/p100 complex, 52 kDa subunit; non-POU domain-containing octamer (ATGCAAAT) binding protein; |
Gene ID : | 4841 |
mRNA Refseq : | NM_001145408 |
Protein Refseq : | NP_001138880 |
MIM : | 300084 |
UniProt ID : | Q15233 |
Chromosome Location : | Xq13.1 |
Pathway : | Circadian rhythm pathway, organism-specific biosystem; mRNA processing, organism-specific biosystem; |
Function : | DNA binding; RNA binding; identical protein binding; nucleotide binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
NONO-2496H | Recombinant Human NONO Protein, His-tagged | +Inquiry |
NONO-2497H | Recombinant Human NONO Protein, His tagged, Avi-Biotinylated | +Inquiry |
Nono-4458M | Recombinant Mouse Nono Protein, Myc/DDK-tagged | +Inquiry |
NONO-2496HB | Recombinant Human NONO Protein, His tagged, Avi-Biotinylated | +Inquiry |
NONO-3679R | Recombinant Rat NONO Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NONO-3766HCL | Recombinant Human NONO 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThis protein is widely expressed in a variety of tissues and organs, including the brain, heart, liver, kidneys, and muscles.
Yes, NONO protein is involved in the regulation of RNA splicing and plays an important role in the splicing process by interacting with other proteins.
NONO protein is expressed in the liver and is involved in the regulation of signaling pathways related to liver function. However, further research is needed to determine its specific role.
NONO protein interacts with DNA repair-related proteins and is involved in the repair process of DNA double-strand breaks.
The protein has been implicated in some neurological diseases, such as motor neuron disease, but its specific role and mechanism still need to be further studied.
NONO protein has been implicated in a variety of diseases, including leukemia, neurological diseases such as motor neuron disease, and progeria.
Customer Reviews (3)
Write a reviewThe stability of NONO has good adaptability under different temperature and pH conditions.
NONO has important application value in the field of drug research and development, and has achieved certain research results.
Experiments with NONO are easy to use and do not require complex procedures.
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