Recombinant Human NOP10 Protein, His-tagged

• Cat.No.: NOP10-1158H
• Product Overview: Recombinant human NOP10 protein, fused to His tag at N-terminus, was expressed in E. coli.

Specification

• Description: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq, Jul 2008].
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
• Molecular Mass: 7.5 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NOP10 NOP10 ribonucleoprotein [ Homo sapiens (human) ]
• Official Symbol: NOP10
• Synonyms: DKCB1; NOLA3; NOP10P
• Gene ID: 55505
• mRNA Refseq: NM_018648
• Protein Refseq: NP_061118
• MIM: 606471
• UniProt ID: Q9NPE3