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Recombinant Human NOS2 protein, His & T7-tagged

Cat.No. : NOS2-7796H
Product Overview : Recombinant Human NOS2 aa. (Thr734~Gly966 (Accession # P35228)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 29.7kDa
Protein length : Thr734~Gly966 (Accession # P35228)
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 8.2.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : NOS2 nitric oxide synthase 2 [ Homo sapiens (human) ]
Official Symbol : NOS2
Synonyms : NOS2; nitric oxide synthase 2; NOS; INOS; NOS2A; HEP-NOS; nitric oxide synthase, inducible; NOS, type II; hepatocyte NOS; inducible NO synthase; inducible NOS; nitric oxide synthase 2, inducible; nitric oxide synthase 2A (inducible, hepatocytes); nitric oxide synthase, macrophage; peptidyl-cysteine S-nitrosylase NOS2
Gene ID : 4843
mRNA Refseq : NM_000625.4
Protein Refseq : NP_000616.3
UniProt ID : P35228

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does genetic variation in the NOS2 gene impact clinical outcomes? 02/09/2023

Genetic polymorphisms in the NOS2 gene have been associated with susceptibility to certain diseases and can influence individual response to treatment.

Are there any clinical biomarkers associated with NOS2 protein expression? 11/11/2022

Certain inflammatory markers and nitric oxide levels can be associated with NOS2 protein expression in clinical settings.

How does NOS2 protein contribute to the pathogenesis of infectious diseases? 05/07/2020

NOS2 protein plays a role in the host defense against pathogens by generating nitric oxide to inhibit microbial growth.

Can NOS2 protein be a potential therapeutic target in inflammatory diseases? 08/21/2017

Can NOS2 protein expression be used to monitor response to treatment in clinical trials? 02/18/2017

Monitoring changes in NOS2 protein expression may provide insights into treatment response and help evaluate therapeutic efficacy in clinical trials.

Customer Reviews (3)

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Reviews
12/18/2022

    They can provide technical assistance, ensuring optimal utilization of the product.

    11/09/2016

      This unique capability to selectively bind to exposed PS simplifies the identification and quantification of different cellular populations, reducing experimental errors and enhancing accuracy.

      02/02/2016

        This may include providing detailed protocols, troubleshooting guidance, and access to knowledgeable experts who can answer any inquiries or concerns.

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