Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human NOTCH4 Protein (Met1-Phe637), His-tagged

Cat.No. : NOTCH4-523H
Product Overview : Recombinant Human NOTCH4 Protein (AAH63815.1) (Met1-Phe637) was produced by Baculovirus-Insect Cells expression system. This protein was expressed with a polyhistidine tag at the C-terminus.
  • Specification
  • Gene Information
  • Related Products
Description : Notch4 belongs to a family of transmembrane receptors that play an important role in vascular development and maintenance.The NOTCH4 gene, located within the MHC region, is involved in cellular differentiation and has varying effects dependent on tissue type.NOTCH4 regulates signaling pathways associated with neuronal maturation, a process involved in the development and patterning of the central nervous system. The NOTCH4 gene is located at 6p21.3 and involved in the development and patterning of the central nervous systems. The NOTCH4 gene has also been identified as a possible susceptibility gene for schizophrenia (SCZ).
Source : Baculovirus-Insect Cells
Species : Human
Tag : His
Predicted N Terminal : Arg 24
Form : Lyophilized from sterile 20 mM PB, 500 mM NaCl, pH 7.0, 10 % glycerol. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human NOTCH4 consists 625 amino acids and predicts a molecular mass of 66.1 kDa.
Protein length : Met1-Phe637
Endotoxin : < 1.0 EU per μg protein as determined by the LAL method.
Purity : > 90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Publication :
The Special Role of JAK/STAT, and Notch Signaling Pathways in Cancer Pathogenesis (2023)
Gene Name : NOTCH4 notch 4 [ Homo sapiens ]
Official Symbol : NOTCH4
Synonyms : NOTCH4; notch 4; Notch homolog 4; INT3; NOTCH3; FLJ16302; MGC74442;
Gene ID : 4855
mRNA Refseq : NM_004557
Protein Refseq : NP_004548
MIM : 164951
UniProt ID : Q99466

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NOTCH4 Products

Required fields are marked with *

My Review for All NOTCH4 Products

Required fields are marked with *

0

Inquiry Basket

cartIcon
logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends