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Recombinant Human NPPB protein, His & GST-tagged

Cat.No. : NPPB-893H
Product Overview : Recombinant Human NPPB fused with His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
Source : E. coli
Species : Human
Tag : His & GST
Purity : ≥ 85% (SDS-PAGE)
Applications : ELISA
Storage : Aliquot and store at -20 or -80 ℃. Avoid repeated freeze/thaw cycles
Storage buffer : 1×PBS Buffer, Sarkosyl (0.15% m/v)
Gene Name : NPPB natriuretic peptide B [ Homo sapiens (human) ]
Official Symbol : NPPB
Synonyms : BNP; brain type natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; natriuretic protein
Gene ID : 4879
mRNA Refseq : NM_002521.2
Protein Refseq : NP_002512.1
UniProt ID : P16860

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In what ways does NPPB protein contribute to the understanding of fluid overload in patients? 04/20/2022

Elevated NPPB levels are associated with fluid overload, providing valuable information for clinicians in managing patients with conditions like edema.

Can NPPB protein be used in monitoring the efficacy of treatments for cardiovascular diseases? 03/02/2020

Yes, monitoring NPPB levels over time can help assess the effectiveness of treatments and interventions in managing cardiovascular conditions.

How do age and gender influence the normal range of NPPB protein levels in healthy individuals? 04/25/2019

Normal ranges of NPPB may vary with age and gender. Understanding these variations is essential for accurate clinical interpretation.

Are there any specific contraindications or limitations in using NPPB protein as a clinical marker? 11/26/2016

While NPPB is a valuable marker, clinicians should consider factors like renal function and comorbidities that may affect its interpretation.

How does NPPB protein influence the management of hypertension in clinical practice? 06/11/2016

NPPB regulates blood pressure by promoting vasodilation and natriuresis. Understanding its levels can guide the management of hypertension.

Customer Reviews (3)

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Reviews
06/17/2022

    They actively engage with researchers, comprehending their specific experimental needs, and offering tailored services accordingly.

    01/16/2022

      This collaborative partnership facilitates a seamless and efficient research process, as the manufacturer aligns their support and services with my unique requirements.

      12/09/2019

        The manufacturer's excellent technical support, commitment to innovation, and customer-centric approach further reinforce its suitability for my research.

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