Recombinant Human NPR3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NPR3-4241H
• Product Overview: NPR3 MS Standard C13 and N15-labeled recombinant protein (NP_000899) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 59.6 kDa
• AA Sequence: MPSLLVLTFSPCVLLGWALLAGGTG GGGVGGGGGGAGIGGGRQEREALPP QKIEVLVLLPQDDSYLFSLTRVRPA IEYALRSVEGNGTGRRLLPPGTRFQ VAYEDSDCGNRALFSLVDRVAAARG AKPDLILGPVCEYAAAPVARLASHW DLPMLSAGALAAGFQHKDSEYSHLT RVAPAYAKMGEMMLALFRHHHWSRA ALVYSDDKLERNCYFTLEGVHEVFQ EEGLHTSIYSFDETKDLDLEDIVRN IQASERVVIMCASSDTIRSIMLVAH RHGMTSGDYAFFNIELFNSSSYGDG SWKRGDKHDFEAKQAYSSLQTVTLL RTVKPEFEKFSMEVKSSVEKQGLNM EDYVNMFVEGFHDAILLYVLALHEV LRAGYSKKDGGKIIQQTWNRTFEGI AGQVSIDANGDRYGDFSVIAMTDVE AGTQEVIGDYFGKEGRFEMRPNVKY PWGPLKLRIDENRIVEHTNSSPCKS CGLEESAVTGIVVGALLGAGLLMAF YFFRKKYRITIERRTQQEESNLGKH RELREDSIRSHFSVATRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NPR3 natriuretic peptide receptor 3 [ Homo sapiens (human) ]
• Official Symbol: NPR3
• Synonyms: NPR3; natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C); ANPRC, C5orf23, chromosome 5 open reading frame 23, NPRC; atrial natriuretic peptide receptor 3; FLJ14054; GUCY2B; atrial natriuretic peptide receptor type C; atrial natriuretic peptide clearance receptor; NPRC; ANP-C; ANPRC; NPR-C; ANPR-C; C5orf23; MGC22189
• Gene ID: 4883
• mRNA Refseq: NM_000908
• Protein Refseq: NP_000899
• MIM: 108962
• UniProt ID: P17342