Recombinant Human NR0B1 Protein, GST-tagged

• Cat.No.: NR0B1-6064H
• Product Overview: Human NR0B1 full-length ORF ( NP_000466.2, 1 a.a. - 470 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that contains a DNA-binding domain. The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor. This protein also functions as an anti-testis gene by acting antagonistically to Sry. Mutations in this gene result in both X-linked congenital adrenal hypoplasia and hypogonadotropic hypogonadism. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 78.1 kDa
• AA Sequence: MAGENHQWQGSILYNMLMSAKQTRA APEAPETRLVDQCWGCSCGDEPGVG REGLLGGRNVALLYRCCFCGKDHPR QGSILYSMLTSAKQTYAAPKAPEAT LGPCWGCSCGSDPGVGRAGLPGGRP VALLYRCCFCGEDHPRQGSILYSLL TSSKQTHVAPAAPEARPGGAWWDRS YFAQRPGGKEALPGGRATALLYRCC FCGEDHPQQGSTLYCVPTSTNQAQA APEERPRAPWWDTSSGALRPVALKS PQVVCEAASAGLLKTLRFVKYLPCF QVLPLDQQLVLVRNCWASLLMLELA QDRLQFETVEVSEPSMLQKILTTRR RETGGNEPLPVPTLQHHLAPPAEAR KVPSASQVQAIKCFLSKCWSLNIST KEYAYLKGTVLFNPDVPGLQCVKYI QGLQWGTQQILSEHTRMTHQGPHDR FIELNSTLFLLRFINANVIAELFFR PIIGTVSMDDMMLEMLCTKI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NR0B1 nuclear receptor subfamily 0, group B, member 1 [ Homo sapiens ]
• Official Symbol: NR0B1
• Synonyms: NR0B1; nuclear receptor subfamily 0, group B, member 1; AHC, dosage sensitive sex reversal , DSS; nuclear receptor subfamily 0 group B member 1; AHCH; DAX1; nuclear receptor DAX1; nuclear receptor DAX-1; nuclear hormone receptor; DSS-AHC critical region on the X chromosome protein 1; AHC; AHX; DSS; GTD; HHG; DAX-1; NROB1; SRXY2
• Gene ID: 190
• mRNA Refseq: NM_000475
• Protein Refseq: NP_000466
• MIM: 300473
• UniProt ID: P51843