Recombinant Human NR1H2, GST-tagged

• Cat.No.: NR1H2-115H
• Product Overview: Recombinant Human GST-tagged Liver X receptor beta ligand-binding domain (LXRB-LBD) consists of a 218 a.a. GST tag, a 13 a.a. flexible linker and a 266 a.a. LXRB-LBD, Acc# AAH74500.1, amino acids 196-461, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: Liver X receptor beta (LXR-β or LXRB) is encoded by the NR1H2 gene (nuclear receptor subfamily 1, group H, member 2).
• Form: 20 mM Na-P pH 8.0, 40 mM KCl, 7 mM reduced glutathione, 15% glycerol.
• Purity: >90%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: NR1H2 nuclear receptor subfamily 1, group H, member 2 [ Homo sapiens ]
• Official Symbol: NR1H2
• Synonyms: NR1H2; nuclear receptor subfamily 1, group H, member 2; ubiquitously expressed nuclear receptor , UNR; oxysterols receptor LXR-beta; liver X receptor beta; LXR b; NER; NER I; RIP15; LX receptor beta; nuclear receptor NER; liver X nuclear receptor beta; nuclear orphan receptor LXR-beta; steroid hormone-nuclear receptor NER; ubiquitously-expressed nuclear receptor; UNR; LXRB; LXR-b; NER-I; FLJ17564
• Gene ID: 7376
• mRNA Refseq: NM_001256647
• Protein Refseq: NP_001243576
• MIM: 600380
• UniProt ID: P55055
• Chromosome Location: 19q13.3
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem
• Function: DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; retinoid X receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; zinc ion binding