Recombinant Human NR2C1 Protein, GST-tagged

• Cat.No.: NR2C1-6077H
• Product Overview: Human NR2C1 full-length ORF ( NP_001027458.1, 1 a.a. - 467 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.6 kDa
• AA Sequence: MATIEEIAHQIIEQQMGEIVTEQQT GQKIQIVTALDHNTQGKQFILTNHD GSTPSKVILARQDSTPGKVFLTTPD AAGVNQLFFTTPDLSAQHLQLLTDN SPDQGPNKVFDLCVVCGDKASGRHY GAVTCEGCKGFFKRSIRKNLVYSCR GSKDCIINKHHRNRCQYCRLQRCIA FGMKQDSVQCERKPIEVSREKSSNC AASTEKIYIRKDLRSPLTATPTFVT DSESTRSTGLLDSGMFMNIHPSGVK TESAVLMTSDKAESCQGDLSTLANV VTSLANLGKTKDLSQNSNEMSMIES LSNDDTSLCEFQEMQTNGDVSRAFD TLAKALNPGESTACQSSVAGMEGSV HLITGDSSINYTEKEGPLLSDSHVA FRLTMPSPMPEYLNVHYIGESASRL LFLSMHWALSIPSFQALGQENSISL VKAYWNELFTLGLAQCWQVMNVATI LATFVNCLHNSLQQAEG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NR2C1 nuclear receptor subfamily 2, group C, member 1 [ Homo sapiens ]
• Official Symbol: NR2C1
• Synonyms: NR2C1; nuclear receptor subfamily 2, group C, member 1; TR2; nuclear receptor subfamily 2 group C member 1; TR2 11; orphan nuclear receptor TR2; TR2 nuclear hormone receptor; nuclear receptor subfamily 2, group C isoform
• Gene ID: 7181
• mRNA Refseq: NM_001032287
• Protein Refseq: NP_001027458
• MIM: 601529
• UniProt ID: P13056