Recombinant Human NRXN3 Protein, His-tagged

• Cat.No.: NRXN3-2513H
• Product Overview: Recombinant Human NRXN3 Protein (Phe28-Ser311) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Phe28-Ser311
• Description: This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 35.7 kDa
  Accurate Molecular Mass: 36 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NRXN3 neurexin 3 [ Homo sapiens (human) ]
• Official Symbol: NRXN3
• Synonyms: NRXN3; neurexin 3; C14orf60, chromosome 14 open reading frame 60; neurexin-3-beta; KIAA0743; neurexin III; neurexin III-beta; neurexin III-alpha; C14orf60; MGC176711
• Gene ID: 9369
• mRNA Refseq: NM_001105250
• Protein Refseq: NP_001098720
• MIM: 600567
• UniProt ID: Q9HDB5