Recombinant Human Nuclear Receptor Subfamily 1, Group I, Member 3, GST-tagged
Cat.No. : | NR1I3-1277H |
Product Overview : | Recombinant human NR1I3, Ligand Binding Domain with GST tag,containing amino acids 101-348. |
- Specification
- Gene Information
- Related Products
Cat. No. : | NR1I3-1277H |
Description : | NR1I3 was identified as amember of the orphan nuclear hormone receptor family in 1994. Althoughconstitutively acitve, it can be further activated by phenobarbitol-likecompounds, the most potent being the synthetic compound TCPOBOP. Uponactivation, NR1I3 regulates the xenobiotic drug metabolizing enzymes,cytochrome P450s. |
Source : | E. coli |
Species : | Human |
Form : | Liquid in 20 mMTris-Cl + 25% glycerol + 100 mM KCl + 1 mM DTT + 0.2 mM EDTA. |
Purity : | > 95%as determined by SDS-PAGE analysis |
Applications : | In vitro transcriptionassays; DNA-protein interaction assays; Protein-protein interaction assays. |
storage : | Stablefor 1 year in working aliquots at -80°C. Avoidrepeated freeze-thaw cycles. |
OfficialSymbol : | NR1I3 |
Pathways : | Gene Expression; Generic TranscriptionPathway; Glucocorticoid receptor regulatory network; Nuclear Receptortranscription pathway; Nuclear Receptors; Nuclear receptors in lipidmetabolism and toxicity |
Gene Name : | NR1I3 nuclear receptor subfamily1, group I, member 3 [ Homo sapiens ] |
Synonyms : | NR1I3; nuclear receptorsubfamily 1, group I, member 3; CAR; CAR1; MB67; MGC97144; MGC97209;MGC150433; constitutive androstane receptor; OTTHUMP00000032246; constitutiveactive receptor; orphan nuclear hormone receptor; constitutive activator ofretinoid response; Nuclear receptor subfamily 1 group I member 3; Orphannuclear receptor MB67; OTTHUMP00000032245 |
Gene ID : | 9970 |
mRNA Refseq : | NM_001077469 |
Protein Refseq : | NP_001070937 |
MIM : | 603881 |
UniProt ID : | Q14994 |
Chromosome Location : | 1q23.3 |
Function : | DNA binding; androgen receptor activity; ligand-dependentnuclear receptor activity; metal ion binding; receptor activity; sequence-specificDNA binding; sequence-specific DNA binding transcription factor activity; steroidhormone receptor activity; thyroid hormone receptor activity; transcriptioncoactivator activity; zinc ion binding |
Products Types
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NR1I3-6182M | Recombinant Mouse NR1I3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NR1I3-2913R | Recombinant Rhesus Macaque NR1I3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Nr1i3-667R | Recombinant Rat Nr1i3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NR1I3-3715HCL | Recombinant Human NR1I3 293 Cell Lysate | +Inquiry |
NR1I3-3717HCL | Recombinant Human NR1I3 293 Cell Lysate | +Inquiry |
NR1I3-3716HCL | Recombinant Human NR1I3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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