Recombinant Human NUDT15 Protein, His-tagged
Cat.No. : | NUDT15-11H |
Product Overview : | Recombinant Human Nucleotide triphosphate diphosphatase NUDT15 with a C-terminal His-tag was produced in Nicotiana benthamiana by Agrobacterium-mediated transient expression. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. |
Source : | Nicotiana benthamiana |
Species : | Human |
Tag : | His |
Form : | Lyophilized |
Molecular Mass : | 19.4 kDa |
Purity : | >95% |
Storage : | Lyophilized materials are stable for up to twelve months from date of receipt at -70 centigrade. It is recommended that reconstituted protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | 20 mM HEPES pH8, 150 mM NaCl, 175 mM Trehalose Dihydrate. |
Gene Name : | NUDT15 nudix hydrolase 15 [ Homo sapiens (human) ] |
Official Symbol : | NUDT15 |
Synonyms : | NUDT15; nudix hydrolase 15; MTH2; NUDT15D; nucleotide triphosphate diphosphatase NUDT15; 8-oxo-dGTPase NUDT15; mutT homolog 2; nucleoside diphosphate-linked to another moiety X hydrolase 15; nudix (nucleoside diphosphate linked moiety X)-type motif 15; probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15; probable 8-oxo-dGTP diphosphatase NUDT15; EC 3.6.1.9 |
Gene ID : | 55270 |
mRNA Refseq : | NM_018283 |
Protein Refseq : | NP_060753 |
MIM : | 615792 |
UniProt ID : | Q9NV35 |
Products Types
◆ Recombinant Protein | ||
Nudt15-4536M | Recombinant Mouse Nudt15 Protein, Myc/DDK-tagged | +Inquiry |
NUDT15-1560H | Recombinant Human NUDT15 Protein, His (Fc)-Avi-tagged | +Inquiry |
NUDT15-6250M | Recombinant Mouse NUDT15 Protein, His (Fc)-Avi-tagged | +Inquiry |
NUDT15-337Z | Recombinant Zebrafish NUDT15 | +Inquiry |
NUDT15-10965M | Recombinant Mouse NUDT15 Protein | +Inquiry |
◆ Lysates | ||
NUDT15-3651HCL | Recombinant Human NUDT15 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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