Recombinant Human NUF2 Protein, GST-Tagged

• Cat.No.: NUF2-1320H
• Product Overview: Human NUF2 full-length ORF (AAH08489, 1 a.a. - 464 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76.78 kDa
• AA Sequence: METLSFPRYNVAEIVIHIRNKILTG ADGKNLTKNDLYPNPKPEVLHMIYM RALQIVYGIRLEHFYMMPVNSEVMY PHLMEGFLPFSNLVTHLDSFLPICR VNDFETADILCPKAKRTSRFLSGII NFIHFREACRETYMEFLWQYKSSAD KMQQLNAAHQEALMKLERLDSVPVE EQEEFKQLSDGIQELQQSLNQDFHQ KTIVLQEGNSQKKSNISEKTKRLNE LKLSVVSLKEIQESLKTKIVDSPEK LKNYKEKMKDTVQKLKNARQEVVEK YEIYGDSVDCLPSCQLEVQLYQKKI QDLSDNREKLASILKESLNLEDQIE SDESELKKLKTEENSFKRLMIVKKE KLATAQFKINKKHEDVKQYKRTVIE DCNKVQEKRGAVYERVTTINQEIQK IKLGIQQLKDAAEREKLKSQEIFLN LKTALEKYHDGIEKAAEDSYAKIDE KTAELKRKMFKMST
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: NUF2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: NUF2
• Synonyms: NUF2; NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae); CDCA1, cell division cycle associated 1; kinetochore protein Nuf2; cancer/testis antigen 106; CT106; NUF2R; hNuf2; hNuf2R; hsNuf2; cell division cycle associated 1; cell division cycle-associated protein 1; CDCA1
• Gene ID: 83540
• mRNA Refseq: NM_031423
• Protein Refseq: NP_113611
• MIM: 611772
• UniProt ID: Q9BZD4