Recombinant Human OCLN protein, MYC/DDK-tagged
Cat.No. : | OCLN-3603H |
Product Overview : | Recombinant Human OCLN, fussed with MYC/DDK tag at C-terminal, was expressed in HEK293 cells. |
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Description : | This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc&DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 59 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Notes : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | OCLN occludin [ Homo sapiens ] |
Official Symbol : | OCLN |
Synonyms : | OCLN; occludin; tight junction protein occludin TM4 minus; tight junction protein occludin; BLCPMG; FLJ08163; FLJ18079; FLJ77961; FLJ94056; MGC34277; |
Gene ID : | 100506658 |
mRNA Refseq : | NM_002538 |
Protein Refseq : | NP_002529 |
MIM : | 602876 |
UniProt ID : | Q16625 |
Chromosome Location : | 5q13.1 |
Pathway : | Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem; Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Pathogenic Escherichia coli infection, organism-specific biosystem; |
Function : | protein binding; structural molecule activity; thiopurine S-methyltransferase activity; |
Products Types
◆ Recombinant Protein | ||
Ocln-425M | Recombinant Mouse Ocln Protein, His-tagged | +Inquiry |
Ocln-4569M | Recombinant Mouse Ocln Protein, Myc/DDK-tagged | +Inquiry |
OCLN-3815R | Recombinant Rat OCLN Protein, His (Fc)-Avi-tagged | +Inquiry |
Ocln-1882M | Recombinant Mouse Ocln Protein, His-tagged | +Inquiry |
OCLN-2523H | Recombinant Human OCLN Protein, His-tagged | +Inquiry |
◆ Lysates | ||
OCLN-3603HCL | Recombinant Human OCLN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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