Recombinant Human OPA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human OPA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : OPA1-3996H
Product Overview : OPA1 MS Standard C13 and N15-labeled recombinant protein (NP_570845) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 109.4 kDa
AA Sequence : MWRLRRAAVA CEVCQSLVKH SSGIKGSLPL QKLHLVSRSI YHSHHPTLKL QRPQLRTSFQ QFSSLTNLPL RKLKFSPIKY GYQPRRNFWP ARLATRLLKL RYLILGSAVG GGYTAKKTFD QWKDMIPDLS EYKWIVPDIV WEIDEYIDFG HKLVSEVIGA SDLLLLLGSP EETAFRATDR GSESDKHFRK VSDKEKIDQL QEELLHTQLK YQRILERLEK ENKELRKLVL QKDDKGIHHR KLKKSLIDMY SEVLDVLSDY DASYNTQDHL PRVVVVGDQS AGKTSVLEMI AQARIFPRGS GEMMTRSPVK VTLSEGPHHV ALFKDSSREF DLTKEEDLAA LRHEIELRMR KNVKEGCTVS PETISLNVKG PGLQRMVLVD LPGVINTVTS GMAPDTKETI FSISKAYMQN PNAIILCIQD GSVDAERSIV TDLVSQMDPH GRRTIFVLTK VDLAEKNVAS PSRIQQIIEG KLFPMKALGY FAVVTGKGNS SESIEAIREY EEEFFQNSKL LKTSMLKAHQ VTTRNLSLAV SDCFWKMVRE SVEQQADSFK ATRFNLETEW KNNYPRLREL DRNELFEKAK NEILDEVISL SQVTPKHWEE ILQQSLWERV STHVIENIYL PAAQTMNSGT FNTTVDIKLK QWTDKQLPNK AVEVAWETLQ EEFSRFMTEP KGKEHDDIFD KLKEAVKEES IKRHKWNDFA EDSLRVIQHN ALEDRSISDK QQWDAAIYFM EEALQARLKD TENAIENMVG PDWKKRWLYW KNRTQEQCVH NETKNELEKM LKCNEEHPAY LASDEITTVR KNLESRGVEV DPSLIKDTWH QVYRRHFLKT ALNHCNLCRR GFYYYQRHFV DSELECNDVV LFWRIQRMLA ITANTLRQQL TNTEVRRLEK NVKEVLEDFA EDGEKKIKLL TGKRVQLAED LKKVREIQEK LDAFIEALHQ EKSGPTRTRR LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : OPA1 OPA1 mitochondrial dynamin like GTPase [ Homo sapiens (human) ]
Official Symbol : OPA1
Synonyms : OPA1; optic atrophy 1 (autosomal dominant); dynamin-like 120 kDa protein, mitochondrial; dynamin like guanosine triphosphatase; FLJ12460; KIAA0567; MGM1; mitochondrial dynamin like GTPase; NPG; NTG; optic atrophy protein 1; mitochondrial dynamin-like GTPase; dynamin-like guanosine triphosphatase; mitochondrial dynamin-like 120 kDa protein; largeG;
Gene ID : 4976
mRNA Refseq : NM_130832
Protein Refseq : NP_570845
MIM : 605290
UniProt ID : O60313

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