| Description : |
The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
101.2 kDa |
| AA Sequence : |
MGKAAAPSRGGGCGGRSRGLSSLFT VVPCLSCHTAAPGMSASTSGSGPEP KPQPQPVPEPERGPLSEQVSEAVSE AVPRSEPVSETTSEPEPGAGQPSEL LQGSRPGSESSSGVGAGPFTKAASE PLSRAVGSATFLRPESGSLPALKPL PLLRPGQAKTPLGVPMSGTGTTSSA PLALLPLDSFEGWLLKWTNYLKGYQ RRWFVLGNGLLSYYRNQGEMAHTCR GTINLSTAHIDTEDSCGILLTSGAR SYHLKASSEVDRQQWITALELAKAK AVRVMNTHSDDSGDDDEATTPADKS ELHHTLKNLSLKLDDLSTCNDLIAK HGAALQRSLTELDGLKIPSESGEKL KVVNERATLFRITSNAMINACRDFL ELAEIHSRKWQRALQYEQEQRVHLE ETIEQLAKQHNSLERAFHSAPGRPA NPSKSFIEGSLLTPKGEDSEEDEDT EYFDAMEDSTSFITVITEAKEDRKA EGSTGTSSVDWSSADNVLDGASLVP KGSSKVKRRVRIPNKPNYSLNLWSI MKNCIGRELSRIPMPVNFNEPLSML QRLTEDLEYHHLLDKAVHCTSSVEQ MCLVAAFSVSSYSTTVHRIAKPFNP MLGETFELDRLDDMGLRSLCEQVSH HPPSAAHYVFSKHGWSLWQEITISS KFRGKYISIMPLGAIHLEFQASGNH YVWRKSTSTVHNIIVGKLWIDQSGD IEIVNHKTNDRCQLKFLPYSYFSKE AARKVTGVVSDSQGKAHYVLSGSWD EQMECSKVMHSSPSSPSSDGKQKTV YQTLSAKLLWKKYPLPENAENMYYF SELALTLNEHEEGVAPTDSRLRPDQ RLMEKGRWDEANTEKQRLEEKQRLS RRRRLEACGPGSSCSSEEEKEADAY TPLWFEKRLDPLTGEMACVYKGGYW EAKEKQDWHMCPNIFTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
