Recombinant Human OSTM1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: OSTM1-3891H
• Product Overview: OSTM1 MS Standard C13 and N15-labeled recombinant protein (NP_054747) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
• Molecular Mass: 37.3 kDa
• AA Sequence: MEPGPTAAQRRCSLPPWLPLGLLLWSGLALGALPFGSSPHRVFHDLLSEQQLLEVEDLSLSLLQGGGLGPLSLPPDLPDLDPECRELLLDFANSSAELTGCLVRSARPVRLCQTCYPLFQQVVSKMDNISRAAGNTSESQSCARSLLMADRMQIVVILSEFFNTTWQEANCANCLTNNSEELSNSTVYFLNLFNHTLTCFEHNLQGNAHSLLQTKNYSEVCKNCREAYKTLSSLYSEMQKMNELENKAEPGTHLCIDVEDAMNITRKLWSRTFNCSVPCSDTVPVIAVSVFILFLPVVFYLSSFLHSEQKKRKLILPKRLKSSTSFANIQENSNTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: OSTM1 osteopetrosis associated transmembrane protein 1 [ Homo sapiens (human) ]
• Official Symbol: OSTM1
• Synonyms: OSTM1; osteopetrosis associated transmembrane protein 1; osteopetrosis-associated transmembrane protein 1; GL; HSPC019; grey-lethal osteopetrosis; GAIP-interacting protein N terminus; GIPN; OPTB5
• Gene ID: 28962
• mRNA Refseq: NM_014028
• Protein Refseq: NP_054747
• MIM: 607649
• UniProt ID: Q86WC4